得克萨斯大学西南医学中心是得克萨斯大学体系中的核心成员，是美国著名的生物医学研究中心。原名西南部医学院，成立于1943年，当时是作为战时医院成立的。它是美国顶级的致力于医学教育和生物医学科学研究的研究型大学之一。
想要出国访问学习的小伙伴看过来啦，美国得克萨斯大学西南医学中心、微生物学、癌症生物学方面正在招收访问学者、博士后！51访学网小编每周定时更新最新的访学招聘信息，感谢关注51访学。
A postdoctoral or a visiting scholar fellow position is open in the laboratory of Dr. Chen Yao in the Department of Immunology and the Kidney Cancer Program at the UT Southwestern Medical Center.
The long-term goal of Yao laboratory is to identify molecular and cellular targets that can be harnessed to enhance the efficacy of vaccines and immunotherapies against infectious diseases and cancer.
The Yao lab utilizes systems immunology approaches to identify key regulators of T-cell differentiation and function.
Ongoing projects in the laboratory include:
1) Identify novel molecular regulators of long-term antitumor T cell immunity;
2) Identify biomarkers predicting the clinical outcome of cancer immunotherapy;
3) Dissect the mechanisms involved in the T cell response to chronic viral infections.
Dr. Yao received her PhD degree from the University of Minnesota under the supervision of Daniel Kaplan. She completed her postdoctoral training in the laboratory led by John O’Shea at the National Institutes of Health. Dr. Yao is currently an assistant professor in the Department of Immunology and the Kidney Cancer Program at UT Southwestern Medical Center. Dr. Yao is an awardee of the NIAID New Innovators Awards (DP2) and the CPRIT First-Time, Tenure-Track Faculty Scholar Award.
Relevant publications:
- Yao C*, Lou G, Sun HW, Zhu Z, Sun Y, Chen Z, Chauss D, Moseman EA, Cheng J, D’Antonio MA, Shi W, Shi J, Kometani K, Kurosaki T, Wherry EJ, Afzali B, Gattinoni L, Zhu Y, McGavern DB, O’Shea JJ, Schwartzberg PL, Wu T*. (2021) BACH2 Enforces the Transcriptional and Epigenetic Programs of Stem-Like CD8 T cells. Nature Immunology, (online). DOI:10.1038/s41590-021-00868-7 *corresponding authors.
- Yao C, Sun HW, Lacey NE, Ji Y, Moseman EA, Shih HY, Heuston EF, Kirby M, Anderson S, Chen J, Khan O, Handon R, Reilley J, Fioravanti J, Hu J, Gossa S, Wherry EJ, Gattinoni L, McGavern DB, O'Shea JJ*, Schwartzberg PL*, Wu T*. Single-Cell RNA-Seq Reveals TOX as a Key Regulator of CD8+ T cell Persistence in Chronic Infection. Nature Immunology, 2019 Jul;20(7):890-901. PMID: 31209400
Requirements:
- PhD degree in immunology, microbiology, cancer biology or relevant fields.
- Comfortable working with mice and/or patient samples
- Experience with mouse cancer model is preferred
- Experience with bioinformatics and next-generation sequencing is preferred but not required
Candidates who meet the above criteria are welcome to send their CV, cover letter, and contact information of three referees to Dr. Chen Yao at Chen.Yao@UTSouthwestern.edu
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