此刻开始,赏心悦事
2014年7月,复旦大学张颖/张文宏共同通讯在DNA AND CELL BIOLOGY在线发表了题为“HBx elevates oncoprotein AEG-1 expression to promote cell migration by downregulating miR-375 and miR-136 in malignant hepatocytes”的研究论文(10.1089/dna.2014.2376),文章第一作者赵静( jing zhao音译)。该研究发现,miR-375 和 miR-136具有治疗与乙肝病毒 X 蛋白 (HBx)相关的肝细胞癌 (HCC) 的潜力。
近日,该文章被质疑图片重复使用。
图源pubpeer
一位读者联系了文章的第一作者赵静博士,告知作者图 2F文章的“Ctr”和“HBx+si-1”可能来自同一个样本。作者检查了两张图片后表示:图片确实有问题,是一个粗心的错误。
2021年9月,论文作者对该文章进行了修正,对图片进行了替换,并将更新后的手稿提交给了DNA AND CELL BIOLOGY杂志。
2021年10月,DNA and Cell Biology正式对该论文作出撤稿处理,并称原因在于更新后的实验结果并非是在原始实验产生的。
撤稿全文如下:
RETRACTION NOTICE
Retraction of: HBx Elevates Oncoprotein AEG-1 Expression to Promote Cell Migration by Downregulating miR-375 and miR-136 in Malignant Hepatocytes (10.1089/dna.2014.2376)
DNA and Cell Biology officially retracts the paper entitled, ‘‘HBx Elevates Oncoprotein AEG-1 Expression to Promote Cell Migration by Downregulating miR-375 and miR-136 in Malignant Hepatocytes,’’ by Jing Zhao, Wenjie Wang, Yuxian Huang, Jing Wu, Mingquan Chen, Peng Cui, Wenhong Zhang, and Ying Zhang (DNA and Cell Biology; doi: 10.1089/ dna.2014.2376).
After the journal has published a post-publication correction to the article,1 additional considerations were made after revisiting the recently released guidelines by STM: Advancing Trusted Research.2 These recommendations indicate that replicative experiments should not be permitted if they were not generated at the time of the original experimentation.3[section A2(4)] The Editor and Publisher of DNA and Cell Biology are committed to preserving the scientific literature and the community it serves, and abides by all standard guidelines for, and proper protocols of, scientific publishing.
References
[No author(s) listed]. Correction to: HBx elevates oncoprotein AEG-1 expression to promote cell migration by downregulating miR-375 and miR-136 in malignant hepatocytes by Zhao et al. Epub 2021 Sep 27. doi: 10.1089/dna.2014.2376.correx
Working Group on Image Alterations and Duplications. STM STEC Working Group on Image Alterations and Duplications. https://www.stm-assoc.org/standards-technology/working-group-on-image-alterations-and-duplications/ Last accessed Sept. 29, 2021.
STM Working Group on Image Alteration and Duplication Detection. STM Recommendations for handling image integrity issues. https://osf.io/kgyc6/ Last accessed Sept. 29, 2021.
比起被明确规定为学术不端行为的「抄袭和剽窃(plagiarism)」、「伪造(fabrication)和篡改(falsification)」、「一稿多投(duplicate submission)和重复发表 (repetitive publication)」几类行为,这些「无心之失」并不涉及学术道德败坏的问题,但依然要承受同以上几类行为一样的处理后果。
因此,无论如这位赵博士所说是一个「honest error」,不存在任何刻意的造假行为,还是另有原因,这处错误都同样构成「学术不端」,属于工作失误。
回看期刊对于本事件的处理流程,从勘误到修正再到撤稿,都符合学术规范性要求。
作为「共同通讯作者」之一的张文宏,既然以这个身份署名,就意味着他应该作为论文对外责任的承担者。
这与张文宏医生的名气无关,仅与科研本身的严谨性有关。
期刊本身并不会从撤稿这件事获得好处,频繁撤稿在降低期刊声誉的同时,也让读者质疑该期刊同行评审的权威性。
撤稿行为的根本目的,在于学术规范本身,即以一种认真的态度,对科研负责。
参考消息:
https://www.liebertpub.com/doi/pdf/10.1089/dna.2014.2376.retract
https://www.liebertpub.com/doi/pdf/10.1089/dna.2014.2376.correx
https://pubpeer.com/publications/6C6ED93F0EDAC6471466D462CD1097
医客说
撤稿属于正常现象,没必要因为张教授是通讯作者就大惊小怪,更没必要上纲上线。平常待之即可
【责编】医客君
【文章来源】医客小编综合自科研大匠、Pubpeer;DNA AND CELL BIOLOGY官网;Retraction、丁香园等。
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