Product Profile
Product Name
Integrin beta 4 (phospho Tyr1526) antibody
Antibody Type
Primary Antibodies
Product description
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Rabbit Polyclonal antibody to Integrin beta 4 (phospho Tyr1526)Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen
KLH conjugated Synthesised phosphopeptide derived from mouse ITGB4 around the phosphorylation site of Tyr1526
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB(1:100-500):
Species Reactivity
Mouse
Predicted Reactivity
Guinea pig, Pig
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
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phospho ITGB4 (phospho Tyr1526) Tyr1526
phospho ITGB4 (phospho Tyr1526)
CD104
ITGB4 (phospho Tyr1526) Y1526 phospho
ITGB4 (phospho Tyr1526) Tyr1526 phospho
ITGB4 (phospho Tyr1526) phospho Y1526
ITGB4 (phospho Tyr1526) (Phospho Y1526)
Phospho ITGB4 (
Target
Integrin beta 4 (phospho Tyr1526)
Tissue Specificity
phospho-ITGB4(Tyr1526)
Application
Application
- WB analysis of mouse heart (lane 1) and mouse brain (lane 2) lysates using ITGB4 (phospho Tyr1526) antibody at a dilution of 1:200.
Application Notes
WB(1:100-500):
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and less than 0.09% sodium azide.
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