Product Profile

Product Name

ITGB4 (phospho Tyr1510) Antibody

Antibody Type

Primary Antibodies

Product description

Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity ａnd motility.1) Suzuki S., EMBO J. 9:757-763(1990).

Immunogen

ITGB4 (phospho Tyr1510) antibody was raised against a peptide sequence around phosphorylation site of tyrosine1510 (R-D-Y (p)-S-T) derived from Human ITGB4 .

Key Feature

Clonality

Polyclonal

Isotype

IgG

Host Species

Rabbit

Tested Applications

IHC

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:

Species Reactivity

MouseRat

Concentration

1 mg/ml

Purification

Affinity purified

Target Information

Gene Symbol

ITGB4

Alternative Names

GP150
ITB4
CD104 antigen

Molecular Weight(MW)

202 kDa

Tissue Specificity

The antibody detects endogenous levels of ITGB4 only when phosphorylated at tyrosine 1510.

Database Links

Entrez Gene

3691

Protein Accession

NP_000204.3

Application

Application

Application

  • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using ITGB4 (Phospho-Tyr1510) antibody (left) or the same antibody preincubated with blocking peptide (right).

Application Notes

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:

Additional Information

Form

Liquid

Storage Instructions

Store antibody at -20˚C for up to one year.

Storage Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ ａnd Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol.