吃素的菌群落后,微生物提供的纤维代谢物减少,人体内适应性免疫的关键介质——CD4+ T 细胞的代谢适应性也会随之下降[3]。《自然》子刊的一篇研究发现,仅仅一次切换到“盛宴饮食”的改变,就足以引起短暂的粘膜免疫抑制并抑制全身免疫[3]。这时候,免疫力的暂时性下降就可能让你不敌可乐里的冰块,就着饭菜一冷一热吃下去,你的肚子就要开始折腾了。
[1]David, L. A., Maurice, C. F., Carmody, R. N., Gootenberg, D. B., Button, J. E., Wolfe, B. E., ... & Turnbaugh, P. J. (2014). Diet rapidly and reproducibly alters the human gut microbiome. Nature, 505(7484), 559-563.
[3]Siracusa, F., Schaltenberg, N., Kumar, Y., Lesker, T. R., Steglich, B., Liwinski, T., ... & Gagliani, N. (2023). Short-term dietary changes can result in mucosal and systemic immune depression. Nature immunology, 24(9), 1473-1486.
[4]Fiorentino, E. (2019). The consumption of snacks and soft drinks between meals may contribute to the development and to persistence of gastro-esophageal reflux disease. Medical hypotheses, 125, 84-88.
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