属性

质量水平

100

检测方案

95% (HPLC)

形式

powder

反应适用性

reaction type: Coupling Reactions

杂质

≤17wt. % water

应用

peptide synthesis

储存温度

−20°C

SMILES字符串

[Cl-].COc1nc(OC)nc(n1)[N+]2(C)CCOCC2

InChI

1S/C10H17N4O3.ClH/c1-14(4-6-17-7-5-14)8-11-9(15-2)13-10(12-8)16-3;/h4-7H2,1-3H3;1H/q+1;/p-1

InChI key

BMTZEAOGFDXDAD-UHFFFAOYSA-M

相关类别

肽合成用氨基酸、树脂和试剂

应用

4-(4,6-二甲氧基-1,3,5-三嗪-2-基)-4-甲基吗啉盐酸盐可用作以下转化反应的缩合剂:

  • 羧酸和胺在四氢呋喃中发生缩合反应,产生相应的酰胺。[1][2]
  • 羧酸与醇的酯化反应,产生相应的酯。[3]
  • 在质子溶剂中,将羧酸转化为相应的Weinreb酰胺。[4]

用作溶液和固相肽合成中的羧酸的活化剂;性能优于或相当于畅销的偶联剂[5][6]

Collagen-Based Fillers as Alternatives to Cyanoacrylate Glue for the Sealing of Large Corneal Perforations.

Chameen Samarawickramaet al.

Cornea, 37(5), 609-616 (2017-11-28)

To describe the use of collagen-based alternatives to cyanoacrylate glue for the sealing of acute corneal perforations. A collagen analog comprising a collagen-like peptide conjugated to polyethylene glycol (CLP-PEG) and its chemical crosslinker were tested for biocompatibility. These CLP-PEG hydrogels

Esterification of carboxylic acids with alcohols by 4-(4, 6-dimethoxy-1, 3, 5-triazin-2-yl)-4-methyl-morpholinium chloride (DMTMM).

Kunishima M

Synlett, 1999(08), 1255-1256 (1999)

Tetrahedron, 55, 13159-13159 (1999)