Anti-TGF beta1 antibody Catalog Number：OM641708|antibody|gene|growth|mature|peptide|with

Product Profile

Product Name

Anti-TGF beta1 antibody

Antibody Type

Primary Antibodies

Immunogen

Polypeptide

Key Feature

Clonality

Polyclonal

Isotype

IgG

Host Species

Rabbit

Tested Applications

ELISAIHCWB

WB:1:200-1:2000
IHC:1:200-1:1000

Species Reactivity

GoatHumanMouseRat

Concentration

1mg/ml

Purification

Protein A

Target Information

Gene Symbol

TGFB1

Gene Synonyms

CED
LAP
DPD1
TGFB
IBDIMDE
TGFbeta
TGF-beta1

Gene Full Name

transforming growth factor beta 1

Gene Summary

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment ａnd activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) ａnd a mature peptide, ａnd is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, ａnd a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation ａnd growth, ａnd can modulate expression ａnd activation of other growth factors including interferon gamma ａnd tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, ａnd mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016]

Molecular Weight(MW)

44 kDa（Observed:53 kDa）

Cellular Localization

Extracellular region or secreted

Application