Product Profile
Product Name
FGF4 [D5-7]
Antibody Type
Primary Antibodies
Product description
More
Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, ａnd fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithe-lial ａnd neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) ａnd FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) ａnd FGF-10-FGF-23. Members of the FGF family share 30-55% amino acid sequence identity ａnd similar gene structure, ａnd are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family including four tyrosine kinases, designated Flg (FGFR-1), Bek (FGFR-L), TKF ａnd FGFR-3.
Immunogen
Recombinant protein
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Host Species
Mouse
Tested Applications
WBFC
WB:1:250~1:1000
FC:1:100~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Concentration
2 mg/mL.
Target Information
Alternative Names
More
FGF-4 antibody Fgf4 antibody FGF4_HUMAN antibody Fibroblast growth factor 4 antibody fibroblast growth factor 4 splice isoform antibody HBGF-4 antibody HBGF4 antibody Heparin secretory-transforming protein 1 antibody Heparin-binding growth factor 4 antibody Hst antibody HST-1 antibody HST1 antibody HSTF-1 antibody HSTF1 antibody Human stomach cancer transforming factor from FGF related oncogene antibody K FGF antibody Kaposi Sarcoma Oncogene antibody KFGF antibody KS3 antibody Oncogene HST antibody Transforming protein KS3 antibody
Molecular Weight(MW)
22 kDa
Cellular Localization
Secreted.
Database Links
SwissProt ID
P08620
Application
Application
- Fig1: Western blot analysis of FGF4 on human FGF4 recombinant protein using anti-FGF4 antibody at 1/1,000 dilution.
Application
- Fig2: Western blot analysis of FGF4 on HEK293 (1) ａnd FGF4-hIgGFc transfected HEK293 (2) cell lysate using anti-FGF4 antibody at 1/1,000 dilution.
Application
- Fig3: Flow cytometric analysis of NIH/3T3 cells with FGF4 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
Positive Control
Human FGF4 recombinant protein, FGF4-hIgGFc transfected HEK293 cell lysate, NIH/3T3.
Application Notes
WB:1:250~1:1000
FC:1:100~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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