Product Profile

Product Name

Frizzled 5 antibody

Antibody Type

Primary Antibodies

Product description

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Rabbit Polyclonal to Human Frizzled - 5 ( FZD5 )FZD5 is a Frizzled Receptor that mediates Wnt signaling. FZD5 is associated with limb bud ａnd bone marrow stem cell development. FZD5 contributes to the activated state of fibroblast-like synoviocytes from patients with rheumatoid arthritis. Recently, FZD5 has been implicated in melanoma metastasis through the Wnt5a ａnd PKC pathway. FZD5 has been reported to be expressed in fetal kidney, fetal ａnd adult liver, fetal lung, ａnd adult pancreas. ESTs have been isolated from bone, liver/spleen, placenta, ａnd prostate libraries. FZD5 was cloned from a retina cDNA library.

Immunogen

Synthetic peptide - KLH conjugated

Key Feature

Clonality

Polyclonal

Isotype

IgG

Host Species

Rabbit

Tested Applications

IHC-P

Immunohistochemistry with formalin fixed paraffin embedded tissues. Not tested for other uses. IHC-P: Use at a dilution of 1/100 - 1/200.:

Species Reactivity

Human

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration)

Purification

Affinity purified

Target Information

Gene Synonyms

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601723
Frizzled5
FZD5
HFZ5
Frizzled 5
7855
Q13467
C2orf31
DKFZp434E2135
MGC129692

Target

Frizzled 5

Application

Application

Application

Application Notes

Immunohistochemistry with formalin fixed paraffin embedded tissues. Not tested for other uses. IHC-P: Use at a dilution of 1/100 - 1/200.:

Additional Information

Form

Liquid

Storage Instructions

Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot ａnd store at -20ºC or below. Avoid freeze-thaw cycles.

Storage Buffer

Phosphate buffered saline, pH 7.4 containing 0.01% sodium azide