Product Profile

Product Name

Vav (phospho Tyr174) Antibody

Antibody Type

Primary Antibodies

Product description

More

Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation1) Amarasinghe GK, et al. (2005) Biochemistry; 44 (46): 15257-68. Charvet C, et al. (2005) J Biol Chem; 280 (15): 15289-99. Miura-Shimura Y, et al. (2003) J Biol Chem; 278 (40): 38495-504. Kuhne MR, et al. (2000) J Biol Chem; 275 (3): 2185-90.

Immunogen

Vav (Phospho-Tyr174) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 174 (E-I-Y (p) -E-D) derived from Human Vav.

Key Feature

Clonality

Polyclonal

Host Species

Rabbit

Tested Applications

WB

Western Blot: 1:500~1:1000:

Species Reactivity

HumanMouseRat

Concentration

1 mg/ml

Purification

Affinity purified

Target Information

Gene Symbol

VAV1

Alternative Names

VAV
P53
VAV

Molecular Weight(MW)

95 kDa

Tissue Specificity

This antibody detects endogenous level of Vav only when phosphorylated at tyrosine 174.

Database Links

Entrez Gene

7409

Protein Accession

NP_005419.2

Application

Application

Application

  • Western blot analysis of lysed extracts from Jurkat cells untreated or treated with H2O2 using Vav (Phospho-Tyr174).

Application Notes

Western Blot: 1:500~1:1000:

Additional Information

Form

Liquid

Storage Instructions

Store antibody at -20˚C for up to one year.

Storage Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ ａnd Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol.