Product Profile
Product Name
Vav Antibody
Antibody Type
Primary Antibodies
Product description
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Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.1) Amarasinghe GK, et al. (2005) Biochemistry; 44 (46): 15257-68. Charvet C, et al. (2005) J Biol Chem; 280 (15): 15289-99. Miura-Shimura Y, et al. (2003) J Biol Chem; 278 (40): 38495-504. Kuhne MR, et al. (2000) J Biol Chem; 275 (3): 2185-90.
Immunogen
Vav (Ab-174) antibody was raised against a peptide sequence around aa. 172~176 (E-I-Y-E-D) derived from Human Vav.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
Western Blot: 1:500~1:1000:
Species Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
VAV1
Alternative Names
VAV
Molecular Weight(MW)
95 kDa
Tissue Specificity
This antibody detects endogenous level of total Vav protein.
Database Links
Entrez Gene
7409
Protein Accession
NP_005419.2
Application
Application
- Western blot analysis of lysed extracts from JK cells using Vav (Ab-174).
Application Notes
Western Blot: 1:500~1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store antibody at -20˚C for up to one year.
Storage Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ ａnd Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol.
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