Product Profile
Product Name
PRK2 Antibody (H-80)
Antibody Type
Primary Antibodies
Modification Notes
Rho, the Ras-related small GTPase, is responsible for the regulation of actin-based cytoskeletal structures including stress fibers, focal adhesions ａnd the contractile ring apparatus (1,2). Rho proteins function as molecular switches that are able to turn cytokinesis on ａnd off. Although little is known about signaling downstream of Rho, a host of putative Rho effector proteins have been described, including rhophilin, rhotekin, citron ａnd the serine/threonine kinase, protein kinase N (3-6). Several related Rho-binding proteins have been identified, including the serine/threonine kinases PRK2 (PKC-related kinase 2, also designated PAK-2).
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of PRK2 of mouse, rat ａnd human origin by WB, IP, IF ａnd ELISA; also reactive with additional species, including equine, canine, bovine, porcine ａnd avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epie corresponding to amino acids 71-150 mapping near the N-terminus of PRK2 of human origin
Tissue Specificity
epie corresponding to amino acids 71-150 mapping near the N-terminus of PRK2 of human origin
Database Links
Entrez Gene
5586
Application
Application
- Western blot analysis of PRK2 expression in non-transfected: (A) ａnd human PRK2 transfected: (B) 293T whole cell lysates.
Application
- Western blot analysis of PRK2 expression in K-562 whole cell lysate.
Application Notes
recommended for detection of PRK2 of mouse, rat ａnd human origin by WB, IP, IF ａnd ELISA; also reactive with additional species, including equine, canine, bovine, porcine ａnd avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol.
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