Product Profile
Product Name
Anti-PPP2R4 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIHC
IHC:1:200-1:2000
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
PTPA
Gene Synonyms
PP2A
PR53
PPP2R4
Gene Full Name
protein phosphatase 2 phosphatase activator
Gene Summary
More
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases ａnd is implicated in the negative control of cell growth ａnd division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, ａnd a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B＇/PR61, ａnd B＇＇/PR72 families. These different regulatory subunits confer distinct enzymatic specificities ａnd intracellular localizations to the holozenzyme. The product of this gene belongs to the B＇ family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Molecular Weight(MW)
40KD
Cellular Localization
Cylasm, Nucleus
Application
IHC
- Immunohistochemical analysis of paraffin-em
- bedded bladder cancer tissues using PPP2R4 antibody with DAB staining.
IHC
- Immunohistochemical analysis of paraffin-em
- bedded breast cancer tissues using PPP2R4 antibody with DAB staining.
Application Notes
IHC:1:200-1:2000
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer
Purified antibody in PBS with 0.05% sodium azide.
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