Product Profile
Product Name
PPP2R4 antibody
Antibody Type
Primary Antibodies
Product description
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Rabbit Polyclonal antibody to PPP2R4Protein phosphatase 2A is one of the four major Ser/Thr phosphatases ａnd is implicated in the negative control of cell growth ａnd division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, ａnd a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B＇/PR61, ａnd B＇＇/PR72 families. These different regulatory subunits confer distinct enzymatic specificities ａnd intracellular localizations to the holozenzyme. The product of this gene belongs to the B＇ family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant protein of human PPP2R4
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ICC/IFIHC-PWB
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200:
Species Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
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PR53
PTPA
PP2A
protein phosphatase 2A activator
regulatory subunit 4
Target
PPP2R4
Molecular Weight(MW)
40 kDa (note)
Application
Application
- WB analysis of MCF7 lysates using PPP2R4 antibody.
Application
Application
- IHC-P analysis of human kidney tissue using PPP2R4 antibody at a dilution of 1:200.
Application
- ICC/IF analysis of U2OS cells using PPP2R4 antibody (red) ａnd DAPI (blue).
Application Notes
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200:
Additional Information
Form
Liquid
Storage Instructions
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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