Product Profile
Product Name
NQO1 antibody
Antibody Type
Primary Antibodies
Product description
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Mouse Monoclonal Antibody [4D12] to NQO1This gene is a member of the NAD(P)H dehydrogenase (qui) family ａnd encodes a cylasmic 2-electron reductase. This FAD-binding protein forms homodimers ａnd reduces quis to hydroquis. This protein＇s enzymatic activity prevents the one electron reduction of quis that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, ａnd susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors ａnd is also associated with Alzheimer＇s disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Immunogen
The immunogen corresponding to human NQO1 expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4D12
Host Species
Mouse
Tested Applications
ELISAFACSIHCIHC-PWB
ELISA: 1/10000.:
Species Reactivity
Human
Concentration
1 mg/ml
Purification
Target Information
Gene Synonyms
More
DIA4
QR1
NMOR1
NMORI
DHQU
DTD
Target
NQO1
Molecular Weight(MW)
31 kDa (note)
Application
Application
- ELISA analysis of control antigen ａnd antigen using NQO1 antibody [4D12].
Application
Application
- IHC-P analysis of ovarian cancer tissues using NQO1 antibody [4D12].
Application
- IHC-P analysis of testis tissues using NQO1 antibody [4D12].
Application
- WB analysis of (1) A549, (2) SKNES, (3) HepG2, (4) MCF-7 ａnd (5) HeLa lysates using NQO1 antibody [4D12].
Application
- WB analysis of human NQO1 (a.a. 134-274) recombinant protein using NQO1 antibody [4D12].
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
4°C; -20°C for long term storage
Storage Buffer
Ascitic fluid containing 0.03% sodium azide.
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