Product Profile
Product Name
NQO1 Antibody (C-term)
Antibody Type
Primary Antibodies
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WBIHC
WB~~1:50~100 IHC~~1:50~100:
Species Reactivity
Human
Concentration
1 mg/ml
Purification
Target Information
Gene Synonyms
DIA4
NMOR1
Alternative Names
More
NQO1
DIA4
NMOR1
NAD(P)H dehydrogenase [qui] 1
Azoreductase
DT-diaphorase
Menadione reductase
NAD(P)H:qui oxidoreductase 1
Phylloqui reductase
Qui reductase 1
Molecular Weight(MW)
30868 Da
Function
The enzyme apparently serves as a qui reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis
Tissue Specificity
This NQO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245~274 amino acids from the C-terminal region of human NQO1.
Cellular Localization
Cylasm.
Database Links
Entrez Gene
1728
Application
Application
- Western blot analysis of NQO1 Antibody (C-term) in NCI-H460, MCF-7 cell line lysates (35ug/lane). NQO1 (arrow) was detected using the purified Pab.
Application
- NQO1 Antibody (C-term) IHC analysis in formalin fixed ａnd paraffin embedded human Lung carcinoma followed by peroxidase conjugation of the secondary antibody ａnd DAB staining. This data demonstrates the use of the NQO1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes
WB~~1:50~100 IHC~~1:50~100:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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