从晚期二线到一线,EGFR/MET双特异性抗体埃万妥单抗正在重塑EGFR突变晚期非小细胞肺癌的治疗路径,为"慢病化"管理目标提供全新解决方案!

*以下内容仅供医疗卫生专业人士浏览。

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参考文献:

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[9] Riihimaki M, Hemminki A, Fallah M, et al. Metastatic sites and survival in lung cancer [J] . Lung Cancer,2014,86(1):78 -84.

[10] Paul Stockhammer, Michael Grant, Anna Wurtz, et al. Co-Occurring Alterations in Multiple Tumor Suppressor Genes Are Associated With Worse Outcomes in Patients With EGFR-Mutant Lung Cancer[J]. J Thorac Oncol. 2024 Feb;19(2):240-251.

[11] E Felip, B C Cho, V Gutiérrez, et al. Amivantamab Plus Lazertinib vs Osimertinib in First-line EGFR-mutant Advanced NSCLC: Longer Follow-up of the MARIPOSA Study[J]. Ann Oncol. 2024 Sep;35(9):805-816..

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[13] Felip E, B C Cho, V Gutiérrez, et al. Amivantamab plus lazertinib versus osimertinib in first-line EGFR-mutant advanced non-small-cell lung cancer with biomarkers of high-risk disease: a secondary analysis from MARIPOSA[J]. Ann Oncol. 2024;35(9):805-816.

[14] Alexander I Spira, Luis Paz-Ares, Ji-Youn Han, et al. Preventing Infusion-Related Reactions With Intravenous Amivantamab-Results From SKIPPirr, a Phase 2 Study: A Brief Report[J]. J Thorac Oncol. 2025 Jun;20(6):809-816.

[15] Nicolas Girard, Weimin Li, Alexander I Spira, et al. Preventing Moderate to Severe Dermatologic Adverse Events in First-lineEGFR-mutant Advanced NSCLC Treated with Amivantamab Plus Lazertinib. 2025 ELCC. 10MO.

审批编码:CP-556188

批准分发日期:12/6/2025

有效期:12/6/2026

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