异维A酸 4759-48-2

产品信息

中文名

异维A酸

中文同义

维A酸(维甲酸);13-顺式视黄酸;13-顺维生素A酸;保肤灵;异维甲酸;标准品;异曲替酯;异维A酸原料药

英文名

Isotretinoin

英文同义

Tretinoin Impurity 1（Tretinoin EP Impurity A）;Anti Acne Powerful Isotretinoin Powder Isotretinoin Pharmaceutical Raw Materials;Isotretinoin Capsules;Isotretinoin-D5/13-cis-Retinoic acid-D5;Roaccutan;(2Z,4E,6E,8E)-3,7-diMethyl-9-(2,6,6-triMethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid;ISOTRETINON;A different diMension acid

CAS

4759-48-2

分子式

C20H28O2

分子量

EINECS

225-296-0

相关类别

Dermatosis皮肤美容类;抗肿瘤类药物;医药与生物化工;其他化工产品;化工中间体;医药化工类;生发洗护系列;原料药;医药原料药;代谢;小分子抑制剂;皮肤用药;其它药物;药物;BUSPAR;化工原料;Other APIs;皮肤科用药;专科用药;医药中间体;中间体;intermediates;原料;医药原料;抗病毒抗感染类;维生素类;化合物：原料药;角质溶解药;化妆品原料;功能性原料;常规原药系列;有机原料;分析试剂-对照品;Antibiotics;Organic acids;APIs;Intermediates & Fine Chemicals;Pharmaceuticals;Retinoids;API

结构式

性质

熔点

172-175 °C(lit.)

沸点

381.66°C (rough estimate)

密度

1.0597 (rough estimate)

折射率

1.4800 (estimate)

储存条件

−20°C

溶解度

Practically insoluble in water, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). It is sensitive to air, heat and light, especially in solution. Carry out all operations as rapidly as possible and avoid exposure to actinic light; use freshly prepared solutions.

酸度系数(pKa)

4.76±0.33(Predicted)

形态

Fine Crystalline Powder

颜色

Yellow-orange to orange

水溶解性

insoluble

最大波长(λmax)

354nm(EtOH)(lit.)

Merck

14,5228

稳定性

Stable, but probably air and light sensitive. Combustible. Incompatible with strong oxidizing agents.

InChIKey

SHGAZHPCJJPHSC-YCNIQYBTSA-N

EPA化学物质信息

Isotretinoin (4759-48-2)

category：精细化学|