腰痛与退变、肥胖和吸烟等多种因素相关！

维生素D和腰痛相关吗？

Zadro等研究显示，维生素D缺乏与腰痛相关。

Lakkireddy等的研究指出，除了其他已知原因外，维生素D缺乏也可能是机械性腰痛的潜在致病因素。

Kanaujia等的研究表明，慢性非特异性腰痛患者疼痛程度与维生素D缺乏之间呈负相关。

Çalık等的研究显示，维生素D缺乏可能导致慢性腰痛患者功能下降。

Xu等的研究表明，维生素D缺乏与绝经后女性椎间盘退变和腰痛发生率相关。

Panwar等的研究结果表明，维生素D缺乏严重程度的增加可能与慢性腰痛和亚急性腰痛相关。

Gokcek等的研究指出，腰痛患者的疼痛严重程度随着维生素D缺乏增加而增加。

补充维生素D对腰痛有效吗？

Lakkireddy等的研究指出，补充维生素D可有效避免腰痛不断加重。

Ghai等的研究显示，维生素D缺乏与腰痛患者功能障碍增加之间存在显著的正相关。

Ghai等的研指出，缺乏维生素D的慢性腰痛的患者补充维生素D有助于疼痛缓解和功能改善。

Krasowska等的研究认为，补充维生素D有助于降低接受PLIF手术的腰痛患者围手术期疼痛。

Schwalfenberg等的研究指出，缺乏维生素D的慢性腰痛患者，将维生素D补充到正常水平可改善生活质量，甚至可使症状完全消失。

总结：

●维生素D和多种腰痛密切相关

●补充维生素D有助于腰痛缓解

●补充维生素D有助于腰椎功能改善

参考文献

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[5]Xu HW, Yi YY, Zhang SB, Hu T, Wang SJ, Zhao WD, Wu DS. Does vitamin D status influence lumbar disc degeneration and low back pain in postmenopausal women? A retrospective single-center study. Menopause. 2020 May;27(5):586-592.

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[7]Gokcek E, Kaydu A. Assessment of Relationship between Vitamin D Deficiency and Pain Severity in Patients with Low Back Pain: A Retrospective, Observational Study. Anesth Essays Res. 2018 Jul-Sep;12(3):680-684. doi: 10.4103/aer.AER_96_18. Erratum in: Anesth Essays Res. 2018 Oct-Dec;12(4):970.

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[9]Ghai B, Bansal D, Kapil G, Kanukula R, Lavudiya S, Sachdeva N. High Prevalence of Hypovitaminosis D in Indian Chronic Low Back Patients. Pain Physician. 2015 Sep-Oct;18(5):E853-62.

[10]Ghai B, Bansal D, Kanukula R, Gudala K, Sachdeva N, Dhatt SS, Kumar V. Vitamin D Supplementation in Patients with Chronic Low Back Pain: An Open Label, Single Arm Clinical Trial. Pain Physician. 2017 Jan-Feb;20(1):E99-E105.

[11]Krasowska K, Skrobot W, Liedtke E, Sawicki P, Flis DJ, Dzik KP, Libionka W, Kloc W, Kaczor JJ. The Preoperative Supplementation With Vitamin D Attenuated Pain Intensity and Reduced the Level of Pro-inflammatory Markers in Patients After Posterior Lumbar Interbody Fusion. Front Pharmacol. 2019 May 22;10:527.

[12]Schwalfenberg G. Improvement of chronic back pain or failed back surgery with vitamin D repletion: a case series. J Am Board Fam Med. 2009 Jan-Feb;22(1):69-74.

来源：西安市第三医院