Product Profilea

Product Name

Glutamate receptor 2 (Precursor) Antibody

Antibody Type

Primary Antibodies

Product description

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Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.1) Cull-Candy, S. et al. (2006) Curr. Opin. Neurobiol. 16, 288-297. Hanley JG, et al. (2002) Neuron. 34 (1): 53-67

Immunogen

Glutamate receptor 2 (Precursor) (Ab-880) antibody was raised against a peptide sequence around aa.878~882 (I-E-S-V-K) derived from Human Glutamate receptor 2.

Key Feature

Clonality

Polyclonal

Host Species

Rabbit

Tested Applications

WB

Western Blot: 1:500~1:1000:

Species Reactivity

HumanMouseRat

Concentration

1 mg/ml

Purification

Affinity purified

Target Information

Gene Symbol

GRIA2

Alternative Names

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GLUR2
GLURB
GluA2
HBGR2
GluR-K2
GRIA2
GluR-2
GluR-B
AMPA 2

Molecular Weight(MW)

100 kDa

Tissue Specificity

This antibody detects endogenous level of total Glutamate receptor 2 (Precursor) protein.

Database Links

Entrez Gene

2891

Protein Accession

NP_000817.2

Application

Application

Application

  • Western blot analysis of lysed extracts from mouse brain and rat brain tissue using Glutamate receptor 2 (Precursor) (Ab-880).

Application Notes

Western Blot: 1:500~1:1000:

Additional Information

Form

Liquid

Storage Instructions

Store antibody at -20˚C for up to one year.

Storage Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.